Ardisianone is a component with an alkyl benzoquinone structure that can be isolated from Ardisia virens Kurz and Ardisia compressa tea extract. Ardisianone exhibits potent antileukemic activity, particularly against HL-60 cells, with IC50 values of 1.87 µM (24 h) and 1.67 µM (48 h). Ardisianone induces caspase-dependent apoptosis and triggers pyroptosis. Ardisianone can be used for the study of acute myeloid leukemia (AML)[1].
Molekulargewicht:
406.56
CAS Nummer:
[66398-68-3]
Formel:
C24H38O5
Target-Kategorie:
Apoptosis,Pyroptosis
Anwendungsbeschreibung:
MCE Product type: Natural Products
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