4-OHE ((E)-4-Oxo-2-hexenal) is a mutagen formed by omega-3 lipid peroxidation. 4-OHE reacts with deoxyguanosine, deoxycytidine and 5-methyldeoxycytidine to form covalent adducts. 4-OHE induces apoptosis and exhibits genotoxicity. 4-OHE inhibits the growth of Gram-positive and Gram-negative bacteria, which correlates with its electrophilic reactivity towards nucleophilic biomolecules. 4-OHE is a chemical defense component of Dolycoris baccarum (sloe bug), and acts as a deterrent and toxin against insect predators[1][2][3].
Molekulargewicht:
112.13
Reinheit:
98.97
CAS Nummer:
[2492-43-5]
Formel:
C6H8O2
Target-Kategorie:
Apoptosis,Bacterial
Anwendungsbeschreibung:
MCE Product type: Natural Products
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