Madindoline A, CAS [[184877-64-3]] Preis auf Anfrage
Artikelnummer:
MCE-HY-N14323
Hersteller Artikelnummer:
HY-N14323
Alternativnummer:
MCE-HY-N14323-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Madindoline A is an orally active gp130 antagonist with a KD of 288 µM. Madindoline A inhibits IL-6- and IL-11-induced osteoclastogenesis, suppresses IL-6-stimulated serum amyloid A protein production, inhibits bone resorption and bone loss, and also inhibits IL-6- and IL-11-dependent cell line growth, as well as IL-6-dependent Stat3 tyrosine phosphorylation. Madindoline A is applicable for the research of hormone-dependent postmenopausal osteoporosis[1][2].
Molekulargewicht:
369.45
CAS Nummer:
[184877-64-3]
Formel:
C22H27NO4
Target-Kategorie:
Interleukin Related,STAT
Anwendungsbeschreibung:
MCE Product type: Natural Products
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