Boerelasin E is the first cytochalasan possessing a cis-configured delta21(22) double bond that can be isolated from endophytic fungus Boeremia exigua. Boerelasin E exhibits antiproliferative activity against MCF-7 cells (IC50=20.52 µM) more potent than cisplatin (HY-17394). Boerelasin E inhibits the complete cell division of MCF-7 cells by arresting them in the G2/M phase and inducing apoptosis[1].
Molekulargewicht:
477.59
Formel:
C29H35NO5
Target-Kategorie:
Apoptosis
Anwendungsbeschreibung:
MCE Product type: Natural Products
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