Tryptophan-cholic acid, CAS [[1630745-39-9]]

Produktübersicht

• Artikelname: Tryptophan-cholic acid, CAS [[1630745-39-9]]
• Artikelnummer: MCE-HY-N15721
• Hersteller Artikelnummer: HY-N15721
• Alternativnummer: MCE-HY-N15721-100MG,MCE-HY-N15721-25MG,MCE-HY-N15721-50MG,MCE-HY-N15721-5MG,MCE-HY-N15721-10MG,MCE-HY-N15721-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: Trp-CA

Produktbeschreibung

Tryptophan-cholic acid (Trp-CA) is a microbial amino acid-conjugated bile acid that acts as an endogenous ligand and agonist (EC50=9.6 µM) for the orphan G protein-coupled receptor (GPCR) MRGPRE (Mas-related G protein-coupled receptor family member E). Tryptophan-cholic acid is orally effective but has poor oral absorption and does not cross the blood-brain barrier. Tryptophan-cholic acid promotes the secretion of glucagon-like peptide GLP-1, thereby improving glucose tolerance in diabetic mice. Tryptophan-cholic acid improves glucose tolerance, promotes insulin secretion, and alleviates high-fat diet-induced hepatic steatosis without causing pruritus side effects. Tryptophan-cholic acid is primarily used in research on type 2 diabetes (T2D)[1].

Produkteigenschaften

• Molekulargewicht: 594.78
• Reinheit: 99.75
• CAS Nummer: [1630745-39-9]
• Formel: C35H50N2O6
• Target-Kategorie: GLP Receptor,Orphan GPCR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products