Halofuginone (hydrochloride) (Standard), CAS [[1217623-74-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-N1584BR
Hersteller Artikelnummer:
HY-N1584BR
Alternativnummer:
MCE-HY-N1584BR-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
RU-19110 (hydrochloride) (Standard)
Halofuginone (hydrochloride) (Standard) is the analytical standard of Halofuginone (hydrochloride). This product is intended for research and analytical applications. Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-beta activity. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects[1][2][3][4][5].
