7-O-Galloyl-D-sedoheptulose, CAS [[233690-85-2]] Preis auf Anfrage
Artikelnummer:
MCE-HY-N16527
Hersteller Artikelnummer:
HY-N16527
Alternativnummer:
MCE-HY-N16527-1MG,MCE-HY-N16527-5MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
7-O-Galloyl-D-sedoheptulose is an orally effective polyphenolic compound. 7-O-Galloyl-D-sedoheptulose lowers the serum levels of glucose, leptin, insulin, C-peptide, resistin, TNF-alpha, IL-6, and increases the serum level of adiponectin. 7-O-Galloyl-D-sedoheptulose significantly reduces the levels of ROS and lipid peroxidation products (TBARS) by down-regulating the protein expression of NADPH oxidase subunit Nox-4 and p22phox. 7-O-Galloyl-D-sedoheptulose down-regulates NF-kappaB and related pro-inflammatory factors (COX-2, iNOS), inhibits the phosphorylation of JNK and the activity of its downstream AP-1. 7-O-Galloyl-D-sedoheptulose reduces the expression of TGF-beta1 and fibronectin, indicating its potential in anti-tissue fibrosis. 7-O-Galloyl-D-sedoheptulose can be used for the study of type 2 diabetes and its hepatic and pancreatic complications[1].
Molekulargewicht:
362.29
CAS Nummer:
[233690-85-2]
Formel:
C14H18O11
Target-Kategorie:
AP-1,COX,Interleukin Related,JNK,NADPH Oxidase,NF-kappaB,NO Synthase,Reactive Oxygen Species (ROS),TGF-beta Receptor,TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Natural Products
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