Isostrictiniin, CAS [[1801746-41-7]] Preis auf Anfrage
Artikelnummer:
MCE-HY-N17317
Hersteller Artikelnummer:
HY-N17317
Alternativnummer:
MCE-HY-N17317-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
ITN
Isostrictiniin (ITN) is a polyphenolic compound isolated from Nymphaea candida. It upregulates the expression of Nrf2 and HO-1, while downregulating the expression of Keap1. Isostrictiniin reduces the phosphorylation levels of JNK, ERK1/2, p38, IkappaBalpha, and NF-kappaB p65. Isostrictiniin decreases the levels of pro-inflammatory mediators (IL-1beta, IL-6, TNF-alpha, PGE2). Isostrictiniin alleviates LPS-induced acute lung injury and exerts protective effects against acute alcoholic liver injury. Additionally, isostrictiniin exhibits anti-inflammatory, antioxidant, and anti-fibrotic activities.
