Theasinensin C, CAS [[89013-69-4]] Preis auf Anfrage
Artikelnummer:
MCE-HY-N19420
Hersteller Artikelnummer:
HY-N19420
Alternativnummer:
MCE-HY-N19420-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Theasinensin C is an orally effective renin inhibitor and gut microbiota modulator, with an IC50 of 40.21 µM against renin activity. Theasinensin C selectively enriches Akkermansia muciniphila in the gut microbiota, enhances the Akkermansia muciniphila-mediated hydrolysis of the PTS domain of mucin, drives the accumulation of luminal glutamine and serine, and regulates the gut-kidney-liver glutamine/serine metabolic signaling pathway to promote creatine biosynthesis. Theasinensin C improves cognitive function, reduces pro-inflammatory cytokines, alleviates neuropathological changes and restores intestinal barrier integrity. Theasinensin C can be used in research related to hypertension and neuroinflammation induced by high-fructose diet[1][2].
Molekulargewicht:
610.52
CAS Nummer:
[89013-69-4]
Formel:
C30H26O14
Target-Kategorie:
Bacterial,Interleukin Related,Renin,TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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