Tubulysin D is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin D can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin D displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin D inhibits microtubule/Tubulin polymerization and leads to cell cycle arrest and apoptosis[1][2].
Molekulargewicht:
828.07
CAS Nummer:
[309935-57-7]
Formel:
C43H65N5O9S
Target-Kategorie:
ADC Payload,Microtubule/Tubulin
Anwendungsbeschreibung:
MCE Product type: Natural Products
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