Pimaric acid is a resin acid that has been found in A. cordata and various pines. Pimaric acid exerts anticancer effects via endoplasmic reticulum stress, caspase-dependent apoptosis, cell cycle arrest, and inhibition of cell migration in human ovarian cancer cells. Pimaric acid reduces mRNA expression, protein levels, and promoter activity of matrix metalloproteinase-9 (MMP-9) in TNF-alpha-stimulated human aortic smooth muscle cells (HASMCs)[1][2][3].
Molekulargewicht:
302.45
Reinheit:
98.76
CAS Nummer:
[127-27-5]
Formel:
C20H30O2
Target-Kategorie:
Apoptosis,MMP,NF-kappaB,p38 MAPK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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