Britannilactone diacetate (1,6-O,O-Diacetylbritannilactone, Compound 2) exhibits potential NO inhibition effect. Britannilactone diacetate exhibits activity against NO production induced by LPS in BV-2 microglial cells with the EC50 value of 6.3 µM. Britannilactone diacetate exhibits a favorable blood-brain barriers (BBB) penetration and absorption, distribution, metabolism, excretion, and toxicity (ADMET) property[1].
Molekulargewicht:
350.41
CAS Nummer:
[1286694-67-4]
Formel:
C19H26O6
Target-Kategorie:
NO Synthase
Anwendungsbeschreibung:
MCE Product type: Natural Products
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