Bacopaside I (Standard), CAS [[382148-47-2]] Preis auf Anfrage
Artikelnummer:
MCE-HY-N4246R
Hersteller Artikelnummer:
HY-N4246R
Alternativnummer:
MCE-HY-N4246R-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Bacopaside I (Standard) is the analytical standard of Bacopaside I. This product is intended for research and analytical applications. Bacopaside I is an orally active aquaporin AQP1 inhibitor and PKC modulator with neuroprotective and anticancer activities. Bacopaside I specifically blocks the water channel and cGMP-gated ion channel activities of AQP1 without affecting AQP4, thereby inhibiting the migration of colon cancer cells expressing AQP1. Bacopaside I activates the Akt pathway by interacting with PI3K, specifically inhibits MAO-A, effectively alleviates neuron necrosis and apoptosis induced by oxygen-glucose deprivation, reduces oxidative stress, and regulates the surface expression of neuroreceptors. When combined with Bacopaside II (HY-N6016), Bacopaside I significantly reduces the viability, proliferation and invasion ability of breast cancer cells, and binds to the pregnane X receptor (PXR). Bacopaside I is applicable to the research of colon cancer, breast cancer, vascular dementia, cerebral ischemia and other related diseases[1][2][3][4][5].
Molekulargewicht:
979.13
CAS Nummer:
[382148-47-2]
Formel:
C46H74O20S
Target-Kategorie:
Akt,Apoptosis,Aquaporin,Monoamine Oxidase,PI3K,PKC,Pregnane X Receptor (PXR),Reference Standards
Anwendungsbeschreibung:
MCE Product type: Reference Standards
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