4-Methylesculetin is an orally active coumarin derivative, with potent anti-oxidant and anti-inflammatory activities. 4-Methylesculetin inhibits myeloperoxidase activity. 4-Methylesculetin protects bone resorption by reducing the elevated levels of bone-joint exoglycosidases, cathepsin-D and tartrate resistant acid phosphatases. 4-Methylesculetin ameliorats the upregulated non-enzymatic inflammatory markers like TNF-alpha, IL-1beta, IL-6, COX-2 and PGE2, which is promising for research of inflammatory diseases[1][2].
Molekulargewicht:
192.17
Reinheit:
99.27
CAS Nummer:
[529-84-0]
Formel:
C10H8O4
Target-Kategorie:
Cathepsin,Glutathione Peroxidase,Phosphatase
Anwendungsbeschreibung:
MCE Product type: Natural Products
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