Oxyberberine (Oxyberberin, Berlambine) is an orally effective heme oxygenase HO-1 agonist that can activate antioxidant mechanisms by regulating the PI3K/Akt/AMPK signaling pathway. Oxyberberine induces HO-1 expression, increases SOD and GSH-Px activity, inhibits NF-kappaB-mediated inflammatory responses, and improves insulin sensitivity and glucose metabolism. Oxyberberine has anti-diabetic, neuroprotective, anti-inflammatory and antioxidant effects, and can be used to study type 2 diabetes, traumatic brain injury (TBI) and inflammatory bowel disease[1][2][3].
Molekulargewicht:
351.35
Reinheit:
99.85
CAS Nummer:
[549-21-3]
Formel:
C20H17NO5
Target-Kategorie:
Others
Anwendungsbeschreibung:
MCE Product type: Natural Products
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