Tigloylgomisin H is a lignan isolated from the fruits of S. chinensis, can induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. Tigloylgomisin H functions as a monofunctional inducer that specifically upregulates phase II detoxification enzyme NQO1 through the NF-E2-related factor 2 (Nrf2)-ARE pathway, thus represents a potential liver cancer prevention agent[1].
Molekulargewicht:
500.58
Reinheit:
98.37
CAS Nummer:
[66069-55-4]
Formel:
C28H36O8
Target-Kategorie:
Keap1-Nrf2
Anwendungsbeschreibung:
MCE Product type: Natural Products
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