Licraside, found in Glycyrrhiza glabra, is a Farnesoid X receptor (FXR) activator. Licraside activates FXR to induce upregulation of SHP and BSEP, regulates bile acid homeostasis, reduces elevated biliary and serum TBA, serum ALT, AST, GGT, ALP, and TBIL levels, and attenuates liver histopathological damage. Licraside inhibits factor Xa with an IC50 of 48.54 mM. Licraside can be used for the research of cholestasis and thromboembolic diseases[1][2].
Molekulargewicht:
550.51
Reinheit:
99.95
CAS Nummer:
[29913-71-1]
Formel:
C26H30O13
Target-Kategorie:
Factor Xa,FXR
Anwendungsbeschreibung:
MCE Product type: Natural Products
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