Tubulysin G is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin G can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin G displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin G inhibits microtubule/tubulin polymerization and leads to cell cycle arrest and apoptosis[1][2].
Molekulargewicht:
842.05
CAS Nummer:
[799822-08-5]
Formel:
C43H63N5O10S
Target-Kategorie:
ADC Payload,Microtubule/Tubulin
Anwendungsbeschreibung:
MCE Product type: Natural Products
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