4-Hydroxychalcone (Standard) is the analytical standard of 4-Hydroxychalcone (HY-N7056). This product is intended for research and analytical applications. 4-Hydroxychalcone is a chalcone isolated from licorice root, with hepatoprotective activity. 4-Hydroxychalcone inhibits TNFalpha-induced NF-kappaB activation via proteasome inhibition. 4-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria[1][2][3].
