Cyclic ADP-ribose diammonium (cADPR diammonium) is a potent second messenger for calcium mobilization that is synthesized from NAD+ by an ADP-ribosyl cyclase. Cyclic ADP-ribose diammonium increases cytosolic calcium mainly by Ryanodine receptor-mediated release from endoplasmic reticulum and also by extracellular influx through the opening of TRPM2 channels[1][2][3][4][5].
Molekulargewicht:
575.36
Formel:
C15H27N7O13P2
Target-Kategorie:
Calcium Channel,Endogenous Metabolite,TRP Channel
Anwendungsbeschreibung:
MCE Product type: Natural Products
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