Anhydroerythromycin A is a degradation product of the macrolide antibiotic erythromycin. Anhydroerythromycin A is formed via degradation of erythromycin in acidic aqueous solutions in vitro as well as in vivo. Anhydroerythromycin A is active against S. aureus and B. cereus in vitro (MICs = 12.5 and 6.25 µg/ml, respectively). Anhydroerythromycin A also inhibits steroid 6beta-hydroxylase activity associated with the cytochrome P450 (CYP) isoform CYP3A in human liver microsomes.
Molekulargewicht:
715.91
CAS Nummer:
[23893-13-2]
Formel:
C37H65NO12
Target-Kategorie:
Bacterial,Drug Metabolite
Anwendungsbeschreibung:
MCE Product type: Natural Products
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