Tectol, isolated from Lippia sidoides, exhibits significant activity against human leukemia cell lines HL60 and CEM[1]. Tectol is a farnesyltransferase (FTase) inhibitor with IC50s of 2.09 and 1.73 µM for human and T. brucei FTase, respectively. Tectol inhibits drug-resistant strain of P. falciparum (FcB1) with an IC50 of 3.44 µM[1][2].
Molekulargewicht:
450.53
Reinheit:
99.72
CAS Nummer:
[24449-39-6]
Formel:
C30H26O4
Target-Kategorie:
Farnesyl Transferase,Parasite
Anwendungsbeschreibung:
MCE Product type: Natural Products
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