IKD-8344 is a macrocyclic dilactone originally isolated from an actinomycete species and has diverse biological activities, including anticancer, antimicrobial, and anthelmintic properties. It is cytotoxic to L5178Y murine leukemia cells (IC50=0.54 ng/ml).1 IKD-8344 inhibits growth of the mycelial form of C. albicans (MIC=6.25 µg/mL) and potentiates the activity of polymyxin B against the multidrug-resistant pathogenic bacterium B. cenocepacia.
Molekulargewicht:
845.11
CAS Nummer:
[129046-69-1]
Formel:
C48H76O12
Target-Kategorie:
Fungal
Anwendungsbeschreibung:
MCE Product type: Natural Products
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