Neoaureothin, CAS [[59795-94-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: Neoaureothin, CAS [[59795-94-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-N8504
• Hersteller Artikelnummer: HY-N8504
• Alternativnummer: MCE-HY-N8504-2.5MG,MCE-HY-N8504-500UG
• Hersteller: MedchemExpress
• Kategorie: Kits/Assays
• Alternative Synonym: NSC 260179, Spectinabilin

Produktbeschreibung

Neoaureothin is a bacterial metabolite that has been found in Streptomyces. It is an androgen receptor (AR) antagonist that inhibits binding of dihydrotestosterone (DHT) to ARs (IC50=13 µM) and inhibits DHT-induced expression of prostate-specific antigen in LNCaP cells (IC50=1.75 nM). Neoaureothin is cytotoxic to A549, HCT116, and HepG2 cells (IC50s=34.3, 47, and 37.2 µg/mL, respectively). It also has nematocidal activity against the pine wood nematode B. xylophilus (LC50=0.84 µg/mL) and increases survival of P. densiflora trees inoculated with B. xylophilus.

Produkteigenschaften

• Molekulargewicht: 477.55
• CAS Nummer: [59795-94-7]
• Formel: C28H31NO6
• Target-Kategorie: Bacterial

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Biochemical Assay Reagents