Vinaxanthone (SM-345431) is a potent and selective semaphorin3A, phospholipase C (PLC) and FabI inhibitor, with IC50s of 0.1-0.2 µM and 0.9 mM for semaphorin3A and FabI. Vinaxanthone inhibits the substrate (t-o-NAC thioester) and the cofactor (NADPH) with Kis of 3.1 µM and 1.0 µM, respectively. Vinaxanthone can be used to handle infections caused by multidrug-resistant pathogens[1][2][3].
Molekulargewicht:
576.42
Reinheit:
98.77
CAS Nummer:
[133293-89-7]
Formel:
C28H16O14
Target-Kategorie:
Bacterial,Phospholipase
Anwendungsbeschreibung:
MCE Product type: Natural Products
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