pep2-SVKI is a selective peptide inhibitor. pep2-SVKI inhibits the binding of AMPA-type glutamate receptor (GluA2) (C-terminal PDZ site) to glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP), and C-kinase interacting protein (PICK1). pep2-SVKI increases the amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD). pep2-SVKI can be used to study neurological diseases[1][2][3][4].
Molekulargewicht:
1284.46
CAS Nummer:
[328944-75-8]
Formel:
C60H93N13O18
Target-Kategorie:
iGluR
Anwendungsbeschreibung:
MCE Product type: Peptides
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