Pep2m is a peptide receptor inhibitor. Pep2m inhibits the interaction between the C-terminus of the AMPA-type glutamate receptor (GluA2) subunit and N-ethylmaleimide-sensitive fusion protein (NSF). Pep2m prevents synaptic long-term depression (LTD). Pep2m can reduce postsynaptic currents in neurons, AMPA-mediated currents in cultured hippocampal neurons, and AMPA receptor surface expression[1][2][3][4][5].
Molekulargewicht:
1173.43
CAS Nummer:
[243843-42-7]
Formel:
C49H92N18O13S
Target-Kategorie:
iGluR
Anwendungsbeschreibung:
Peptides
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