Icotrokinra, CAS [[2763602-16-8]]

Produktübersicht

• Artikelname: Icotrokinra, CAS [[2763602-16-8]]
• Artikelnummer: MCE-HY-P10587
• Hersteller Artikelnummer: HY-P10587
• Alternativnummer: MCE-HY-P10587-1MG,MCE-HY-P10587-5MG,MCE-HY-P10587-50MG,MCE-HY-P10587-100MG,MCE-HY-P10587-25MG,MCE-HY-P10587-10MG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: JNJ-77242113, JNJ-2113, PN-235

Produktbeschreibung

Icotrokinra (JNJ-77242113) is an orally available, selective antagonist of the IL-23 receptor. Icotrokinra inhibits IL-23-induced STAT3 phosphorylation in peripheral blood mononuclear cells (IC50=5.6 pM) and inhibits IL-23-induced interferon IFN-gamma production in NK cells with an IC50 of 18.4 pM. Icotrokinra exhibits anti-inflammatory activity in a rat TNBS-induced colitis model. Icotrokinra can be used in the study of psoriasis, psoriatic arthritis, and inflammatory bowel disease[1].

Produkteigenschaften

• Molekulargewicht: 1898.17
• Reinheit: 99.9
• CAS Nummer: [2763602-16-8]
• Formel: C90H120N20O22S2
• Target-Kategorie: IFNAR,Interleukin Related,STAT

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Peptides