Ub4ix is a DUB/26S proteasome inhibitor. Ub4ix can protect K48-linked Ub chains from being chopped up by deubiquitinating enzymes (DUBs) and prevent the proteasomal degradation of Ub-tagged proteins. Ub4ix can reduce the viability of Hela cells and induce apoptosis, with an IC50 value of 1.6 µM[1][2].
Molekulargewicht:
1767.91
Reinheit:
99.32
CAS Nummer:
[2396736-46-0]
Formel:
C84H106N18O23S
Target-Kategorie:
Apoptosis,Deubiquitinase,Proteasome
Anwendungsbeschreibung:
MCE Product type: Peptides
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