CALP2 TFA is a calmodulin (CaM) antagonist (Kd of 7.9 µM) with high affinity for binding to the CaM EF-hand/Ca2+-binding site. CALP2 TFA inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca2+ concentrations. CALP2 TFA potently inhibits of adhesion and degranulation. CALP2 TFA is also a strong activator of alveolar macrophages[1][2][3][4].
Molekulargewicht:
1471.72
Reinheit:
99.79
Formel:
C70H105F3N14O15S
Target-Kategorie:
Calmodulin
Anwendungsbeschreibung:
Peptides
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