RFRP-3 (mouse) is a functional ortholog of avian gonadotropin inhibitory hormone (GnIH), binding to GPR147. RFRP-3 (mouse) reduces Progesterone synthesis by inhibiting FSHR and key enzymes involved in steroidogenesis (P450scc, 3beta-HSD, StAR). RFRP-3 (mouse) induces Apoptosis (increase of p53). RFRP-3 (mouse) also suppresses the ERK signaling pathway. RFRP-3 (mouse) can be used for research of follicular development[1].
Molekulargewicht:
2073.34
Formel:
C91H141N29O25S
Target-Kategorie:
Apoptosis,MDM-2/p53,Neuropeptide FF Receptor,PERK
Anwendungsbeschreibung:
Peptides
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