Breast cancer targeting peptide 18-4, CAS [[1332850-08-4]] Preis auf Anfrage
Artikelnummer:
MCE-HY-P10790
Hersteller Artikelnummer:
HY-P10790
Alternativnummer:
MCE-HY-P10790-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Proteine/Peptide
Breast cancer targeting peptide 18-4 is a KRT1 receptor-targeting peptide, with a Kd of 0.98 µM. The amino acid sequence of Breast cancer targeting peptide 18-4 is WxEAAYQrFL, and it is an analogue of P160 peptide (HY-P10789). When covalently conjugated with the anticancer peptide MccJ25, Breast cancer targeting peptide 18-4 significantly increases the cellular uptake of MccJ25 in breast cancer cells and enhances its anticancer activity. The covalent conjugate exhibits IC50 values of 14.2, 20, and 25 µM against MCF-7, MDA-MB-435, and MDA-MB-435-MDR cells, respectively[1].
Molekulargewicht:
1296.47
CAS Nummer:
[1332850-08-4]
Formel:
C63H89N15O15
Target-Kategorie:
Microtubule/Tubulin
Anwendungsbeschreibung:
Peptides
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