omega-Agatoxin IVA is a potent, selective P/Q type Ca2+ (Cav2.1) channel blocker with IC50 values of 2 nM and 90 nM. omega-Agatoxin IVA inhibits glutamate exocytosis and calcium influx elicited by high potassium. omega-Agatoxin IVA inhibits Capsaicin (HY-10448)-induced CGRP release and vasodilation. omega-Agatoxin IVA can be used for the research of neurological and cardiovascular disease[1][2][3].
Molekulargewicht:
5202.25
Reinheit:
98.71
CAS Nummer:
[145017-83-0]
Formel:
C217H360N68O60S10
Target-Kategorie:
Calcium Channel
Anwendungsbeschreibung:
MCE Product type: Peptides
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