PL120131 is a PD-1/PD-L1 inhibitory peptide that can interfere with the interaction of PD-1/PD-L1 by binding to PD-1. PL120131 is capable of inhibiting the PD-1-mediated apoptotic signaling pathway, protecting Jurkat cells and primary lymphocytes from apoptosis. PL120131 aids in the antitumor activity of cytotoxic T lymphocytes (CTLs)[1].
Molekulargewicht:
1404.61
Formel:
C62H105N19O18
Target-Kategorie:
Apoptosis,PD-1/PD-L1
Anwendungsbeschreibung:
Peptides
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