dCNP binds to NPR-B/C receptor, activates cGMP signaling pathway, and regulates vascular function. dCNP exhibits anti-hypoxia property through downregulation of hypoxia-related genes expressions like HIF1alpha and HIF2alpha. dCNP inhibits the induction of tumor stroma and exhibits anti-fibrosis activity. dCNP upregulates CTLs, NK cells, and conventional type 1 dendritic cells in tumors, and activates immune responses[1].
Molekulargewicht:
3147.91
Reinheit:
95.79
Formel:
C141H248N38O36S3
Target-Kategorie:
Natriuretic Peptide Receptor (NPR)
Anwendungsbeschreibung:
Peptides
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