Zolucatetide (FOG-001,I-66) is a potent beta-catenin inhibitor with an IC50 of beta-catenin and T-cell factor (TCF) transcription factor interaction. Zolucatetide inhibits cell proliferation and induces cell cycle arrest in target cells. Zolucatetide exhibits anti-tumor efficacy in mice bearing COLO320DM colon cancer cell (with APC, TP53 mutations) xenografts. Zolucatetide can be used for the study of colon cancer[1].
Molekulargewicht:
2076.39
Reinheit:
99.31
CAS Nummer:
[3044032-95-0]
Formel:
C102H134N18O25S2
Target-Kategorie:
beta-catenin
Anwendungsbeschreibung:
Peptides
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