PRO20 is a specific and competitive (pro)renin receptor (PRR) antagonist. PRO20 inhibits Prorenin-induced calcium influx with an IC50 value of 81 nmol/L. PRO20 exerts antihypertensive activity by blocking the binding of prorenin to the PRR, inhibiting the activation of the renin-angiotensin system (RAS), and reducing the production of angiotensin II (Ang II). PRO20 is promising for research of antihypertensive agents[1].
Molekulargewicht:
2341.82
Reinheit:
99.16
Formel:
C105H181N31O27S
Target-Kategorie:
Renin
Anwendungsbeschreibung:
MCE Product type: Peptides
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