Ac-DMLD-CMK TFA is a polypeptide targeting the mouse caspase 3-Gsdme signaling pathway. Ac-DMLD-CMK TFA can specifically inhibit the activation of caspase 3 and Gsdme. Ac-DMLD-CMK TFA blocks the cleavage of Gsdme by caspase 3, inhibits the occurrence of pyroptosis, thereby reducing renal tubular epithelial cell injury and the secretion of inflammatory cytokines. Ac-DMLD-CMK TFA reduces the levels of serum creatinine and blood urea nitrogen in mice induced by Cisplatin (HY-17394) and alleviates the deterioration of kidney function. Ac-DMLD-CMK TFA is promising for research of chemotherapy drug-induced nephrotoxicity[1].
Molekulargewicht:
681.08
Reinheit:
98.44
Formel:
C24H36ClF3N4O11S
Target-Kategorie:
Caspase,Pyroptosis
Anwendungsbeschreibung:
MCE Product type: Peptides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
