VSLRGDTRG acetate is a synthetic peptide containing the RGD motif from cadherin 17 (CDH17), which binds to alpha2beta1 integrin and activates its signaling pathway. VSLRGDTRG acetate promotes the high-affinity conformational change of beta1 integrin through the RGD motif, enhancing cell adhesion and phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. VSLRGDTRG acetate can be used in research on cancers expressing CDH17, such as colon cancer and pancreatic cancer[1][2].
Molekulargewicht:
960.05 (free base)
Reinheit:
99.04
Formel:
C38H69N15O14..xC2H4O2
Target-Kategorie:
ERK,FAK,Integrin
Anwendungsbeschreibung:
MCE Product type: Peptides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
