CS-VIP 8 is a selective allosteric WDR5 protein inhibitor (Ki= 0.008 µM). CS-VIP 8 induces conformational changes in the MLL1 complex, leading to the dissociation of MLL1 from the complex, inhibiting MLL1 histone methyltransferase activity and regulating HOX gene expression. CS-VIP 8 is promising for research of hematological diseases such as leukemia[1].
Molekulargewicht:
924.94
Formel:
C43H52F4N12O7
Target-Kategorie:
Histone Methyltransferase,WDR5
Anwendungsbeschreibung:
MCE Product type: Peptides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
