Ac2-26 ammonium is the N-terminal peptide of annexin 1, and has anti-inflammatory activity. Ac2-26 ammonium induces a decrease in IKKbeta protein in lysosomes by chaperone-mediated autophagy (CMA). Ac2-26 ammonium ameliorates lung ischemia-reperfusion injury. Ac2-26 ammonium also inhibits airway inflammation and hyperresponsiveness in an asthma rat model[1][2][3][4].
Molekulargewicht:
3089.43 (free base)
Reinheit:
97.45
Formel:
C141H210N32O44S.xNH3
Target-Kategorie:
IKK
Anwendungsbeschreibung:
Peptides
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