(123B9)2-L2-PTX is an EphA2-agonistic peptide-drug conjugate (PDC). (123B9)2-L2-PTX consists of a dimeric 123B9 (HY-P10579) and Paclitaxel (HY-B0015). (123B9)2-L2-PTX significantly reduces circulating tumor cells and inhibits lung tumor metastasis in breast-cancer-Metastasis mice model. (123B9)2-L2-PTX can be used for cancers research, such as melanomas and ovarian and breast cancers[1].
Molekulargewicht:
4155.16
Formel:
C192H254Cl2F2N34O63
Target-Kategorie:
Ephrin Receptor,Peptide-Drug Conjugates (PDCs)
Anwendungsbeschreibung:
Peptides
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