MMK1 TFA is a potent and selective human formyl peptide receptor like-1 (FPRL-1/FPR2) agonist with EC50s of 10000 nM for FPRL-1 and FPR1, respectively. MMK1 TFA is a potent chemotactic and calcium-mobilizing agonist. MMK1 TFA potently activates phagocytic leukocytes and enhances Pertussis Toxin-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 TFA exerts anxiolytic-like activity[1][2][3][4].
Molekulargewicht:
1610.96 (free acid)
Formel:
C75H123N19O18S.xC2HF3O2
Target-Kategorie:
Calcium Channel,Formyl Peptide Receptor (FPR)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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