Cys-PKHB1 (Cys-txCD47) is a peptide conjugated to PKHB1, a CD47 agonist peptide and a thrombospondin-1 peptide mimic with antitumor effects. PKHB1 induces mitochondrial alterations, ROS generation, intracellular Ca+ accumulation, and calcium-dependent cell death in breast cancer cells. PKHB1 induces immune system activation in breast cancer cells through immunogenic cell death[1][2].
Molekulargewicht:
1487.88
CAS Nummer:
[2378833-51-1]
Formel:
C71H110N18O13S2
Target-Kategorie:
CD47,Reactive Oxygen Species (ROS),Thrombopoietin Receptor
Anwendungsbeschreibung:
Peptides
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