NNC0165-1273 is an analog of gut hormone peptide YY (PYY3-36). NNC0165-1273 has a superior affinity for Y2 receptor over Y1, Y4, and Y5 receptor. NNC0165-1273 has a potent anorectic effect and significantly reduces nighttime and ghrelin-induced food intake by producing early satiety. NNC0165-1273 inhibits ghrelin-induced cFos expression in NPY/AgRP neurons. NNC0165-1273 can be used for antiobesity therapies research[1].
Molekulargewicht:
4136.54
Formel:
C186H280N54O54
Target-Kategorie:
Neuropeptide Y Receptor
Anwendungsbeschreibung:
MCE Product type: Peptides
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