Cyclo(RGDfK(NHS)) is the activated ester form of Cyclo(-RGDfK) (HY-P0023). Cyclo(-RGDfK) is a potent and selective inhibitor of the alphavbeta3 integrin, with an IC50 of 0.94 nM. Cyclo(-RGDfK) potently targets tumor microvasculature and cancer cells through the specific binding to the alphavbeta3 integrin on the cell surface[1][2].
Molekulargewicht:
700.74
Formel:
C31H44N10O9
Target-Kategorie:
Integrin
Anwendungsbeschreibung:
MCE Product type: Peptides
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