ProTx II TFA is a selective blocker of Nav1.7 sodium channels with an IC50 of 0.3 nM, and is at least 100-fold selective for Nav1.7 over other sodium channel subtypes. ProTx-II inhibits sodium channels by decreasing channel conductance and shifting activation to more positive potentials and blocks action potential propagation in nociceptors[1][2].
Molekulargewicht:
3826.59 (free base)
Reinheit:
99.72
Formel:
C168H250N46O41S8.xC2HF3O2
Target-Kategorie:
Sodium Channel
Anwendungsbeschreibung:
MCE Product type: Peptides
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