BAM(8-22) TFA, a proteolytically cleaved product of proenkephalin A and sensory neuron-specific receptor (SNSR) agonist, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1. BAM(8-22) TFA induces scratching in mice in an Mrgpr-dependent manner. In addition, BAM(8-22) TFA has an analgesic effect and can also inhibit the activation of microglia[1].
Formel:
C91H127N25O23S.xC2HF3O2
Target-Kategorie:
Mas-related G-protein-coupled Receptor (MRGPR)
Anwendungsbeschreibung:
MCE Product type: Peptides
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