PR-39 TFA, a natural proline- and arginine-rich antibacterial peptide, is a noncompetitive, reversible and allosteric proteasome inhibitor. PR-39 TFAreversibly binds to the alpha7 subunit of the proteasome and blocks degradation of NF-kappaB inhibitor IkappaBalpha by the ubiquitin-proteasome pathway. PR-39 TFA stimulates angiogenesis, inhibits inflammatory responses and significant reduces myocardial infarct size in mice[1][2].
Molekulargewicht:
4833.76
Reinheit:
99.89
Formel:
C231H347F3N70O42
Target-Kategorie:
Bacterial,Proteasome
Anwendungsbeschreibung:
MCE Product type: Peptides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
