A20FMDV2 is a highly selective alphavbeta6 integrin inhibitor with human IC50 values of 3 nM and binds with at least 1000-fold selectivity over other RGD-binding integrins. A20FMDV2 binds to the integrins RGD-binding site and a hypothesized synergy site, induces rapid integrin internalization, and delays post-internalization integrin recycling to the cell surface. A20FMDV2 can be used for the research of pancreatic cancer, breast cancer, colorectal cancer, ovarian cancer, oral squamous cell carcinoma[1][2].
Molekulargewicht:
2163.48
Reinheit:
99.80
CAS Nummer:
[932699-03-1]
Formel:
C93H163N31O28
Target-Kategorie:
Integrin
Anwendungsbeschreibung:
MCE Product type: Peptides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
